Mechanism of action of anticoagulant drugs. Garlic does interact with anticoagulants to increase their effect. Most important food for a patient taking anticoagulants to avoid. aPtt is the study of choice for heparin therapy. INR is the best and most effective for warfarin therapy. Lab test used to best measure the effectiveness of warfarin sodium therapy. Anticoagulants do prevent the formation of blood clots either by inhibiting specific clotting factors in the coagulation cascade or diminish the clotting action of platelets. Fibrinolysis is the removal of a clot in order to release plasminogen. Heparin and the low-molecular-weight heparin (LMWH) molecules are too large to cross the placental barrier. Rationale for switching warfarin to enoxaparin when she becomes pregnant. Use of heparin during breastfeeding can trigger bleeding from the nipples and should be avoided. Most therapeutic response to a new mother who receives heparin and wants to breast feed. Alteplase (Activase) must be given within 3 hours of a thrombotic cerebro vascular accident (CVA) for maximum effectiveness. Priority question to ask when patient is brought to ER after having a stroke that is verified. Garlic has been shown to decrease the aggregation of platelets, thus producing an anticoagulant effect. Best assessment question to ask to a patient on warfarin, INR is in the high range and patient denies taking any aspirin products. A low blood pressure and red blood cell (RBC) count in the patient could indicate internal bleeding. Best assessment what a patient who is receiving heparin has a low blood pressure and a low red blood cell count.
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